To create comprehensive reference maps of all human cells—the fundamental units of life—as a basis for both understanding human health and diagnosing, monitoring, and treating disease.
The goals of this seminar series are:
The HCA Biological Network Seminar Series is made possible through the generous support of the Chan Zuckerberg Initiative.
10:30-12:00 EST | 15:30-17:00 GMT
Breast Network - Alecia-Jane Twigger
Unravelling the heterogeneity and function of human milk secretory cells using single-cell RNA-sequencing
Liver Network - Sonya MacParland
Mapping the human liver in health and disease with single-cell resolution
10:30-12:00 EST | 15:30-17:00 GMT
Adipose Network - Christian Wolfrum
A single cell approach to adipose plasticity and thermogenesis
Lung Network - Nick Banovich
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity
10:30-12:15 EST | 15:30-17:15 GMT
Organoid Network - Hans Clevers
Adult stem cell-based organoids at single cell resolution
Development Network - Paola Arlotta
Development and disease of the human brain at single cell resolution
10:30-12:00 EDT | 15:30-17:00 BST
Genetic diversity Network - Joseph Powell
Population-scale cellular genomics
Genetic diversity Network - Shyam Prabhakar
Genetic Diversity: New Cohort Studies on Immune Cells
Gut Network - Agne Antanaviciute
Spatiotemporal analysis of human intestinal development at single-cell resolution
10:30-12:00 EDT | 15:30-17:00 BST
Heart Network - Jonathan Seidman
Mapping the cellular complexity of the human heart
Musculoskeletal Network - Chris Buckley
The implications of the Human Cell atlas for Experimental Medicine studies in arthritis
10:30-12:00 EDT | 15:30-17:00 BST
Oral & Craniofacial Network - Paul Sharpe
Data cherry picking and making connections: Telocytes and macrophages in periodontitis
Skin Network - Magnus Lynch
Decoding human skin in health and disease at single-cell resolution
10:30-12:00 EDT | 15:30-17:00 BST
Nervous system Network - Ed Lein
Overview of progress in the Neuro network/BRAIN Initiative Cell Census Network
David Rowitch
High resolution spatial transcriptomics for brain development and disease
10:30-12:00 EST | 15:30-17:00 GMT
Eye Network - Joshua Sanes
Evolution of cell classes and types in the vertebrate retina
Pancreas Network - Klaus Kaestner
Multimodal analysis of the human pancreas in health and disease by the Human Pancreas Analysis Program (HPAP)
10:30-12:00 EST | 15:30-17:00 GMT
Donna Pacicca
Establishing an Atlas of the Developing Skeleton: Single Cell Analysis of Healthy Pediatric Bone and Cartilage
Bruce Aronow
Interactively Exploring the Systems Biology of Cells, Tissues, and Biological Processes Using the ToppCell Datamine
Kathrin Bernt
Pediatric hematopoietic development - opportunities and challenges
Bartha Maria Knoppers
Pediatric Research Ethics: ‘Growing Up’
10:30-12:00 EST | 15:30-17:00 GMT
Andrew Adey
Multimodal profiling
Pratiksha Thakore
Multimodal profiling
Sanja Vickovic
Spatial profiling
Eric Lubeck
Spatial profiling
Ron Germain
Imaging
10:30-12:00 EDT | 15:30-17:00 BST
Reproduction Network - Pauliina Damdimopoulou (Karolinska Institute)
Characterization of human ovaries from birth to menopause
Alain Chédotal (Inserm)
Three-dimensional analysis of sexual differentiation in human embryos
Amander Clark (UCLA)
Development of the Ovary and Testis in Primates
10:30-12:00 EDT | 15:30-17:00 BST
Immune Network - Ramon Massoni (CNAG-CRG)
The periodic table of tonsillar cells
Daniel Rainbow (University of Cambridge)
Developing an Integrated Map of the Immune System in Humans Across Tissues and Ages
Ronald Germain (NIH/NIAID)
New 2D and 3D Imaging and Analytic Methods for Generation of Spatial Tissue Atlases
10:30-12:00 EDT | 15:30-17:00 BST
Kidney Network - Menna Clatworthy (University of Cambridge)
"A 4D Kidney Cell Atlas"
Kidney Network - Matthias Kretzler (University of Michigan)
"Defining the cellular landscape of kidney disease across network and continents"
10:30-12:00 EST | 15:30-17:00 GMT
Wei Kheng Teh
One place for all HCA data - The HCA Data Platform and how we can support the Bionetworks
Alexander Bernier
Practicing Ethics and Data Stewardship in Open Biorepositories
10:30-12:00 EST | 15:30-17:00 GMT
Malte Lücken
Atlas Integration updates
Evan Biederstedt
Cell Annotation Platform updates
10:30-12:00 EDT | 15:30-17:00 BST
Lisa McGinnis (Genentech)
Employing new technologies to interrogate the biology of tumor-associated tertiary lymphoid structures
Alma Andersson (Genentech)
Employing new technologies to interrogate the biology of tumor-associated tertiary lymphoid structures
Sanja Vickovic (NYGC, Columbia University)
Spatial host-microbiome sequencing
Will Hwang (MGH)
Intercellular mechanisms of therapeutic resistance in pancreatic cancer identified by single-cell spatial transcriptomics
Rong Fan (Yale University)
Spatial Multi-Omics Sequencing via Deterministic Barcoding in Tissue