Human Cell Atlas

Data Coordination

These ideas began with an initial proposal by members of EBI, Sanger, and the Broad Institute, and evolved through several discussions at the Chan Zuckerberg Initiative that also included members from CZI and UCSC. A public Google doc version is available at [link] and is open for comments. 

A project of this scale demands a new approach to data coordination.

A wide variety of data must be organized and standardized across a large number researchers. The different components of the architecture — how the data is stored, how it is analyzed, how it is consumed — must be built in a modular fashion, rather than as one monolithic system, to ensure that it can evolve over time. To maximize their use, the data must be open and easily accessible to all researchers, and those researchers should have maximal oppurtunity to innovate. 

An effort is underway to design a modern, cloud-based, modular architecture for organizing and sharing data for the Human Cell Atlas. The key components are detailed below.

  • CloseRead

    Lipsum

    Sequencing data

    Metadata

  • CloseRead

    Overall Architecture

    Key components for a data architecture, including [1] a data ingestion service, [2] a synchronized data store with multiple cloud replicas [3] a collection of secondary analysis pipelines for basic data processing and [4] a collection of tertiary portals for analyses, visualizations, and rich forms of data access.

  • CloseRead

    Data Ingestion

  • CloseRead

    Synchronized Data Store

    Curabitur mauris eros, dapibus eget tincidunt vel, viverra id eros. Pellentesque est nulla, cursus ut sem sed, egestas porta tortor. Quisque euismod, enim vitae volutpat posuere, neque enim ullamcorper est, quis sodales justo sapien sed arcu. Curabitur eget hendrerit felis, nec vehicula orci. Duis odio massa, vulputate faucibus porta eget, blandit vel dui. Curabitur eu varius sem. Etiam dignissim molestie mi et suscipit. Praesent vitae hendrerit odio.

    Nam gravida ornare ex non malesuada. Donec vitae dui non ligula tempor consectetur. Phasellus placerat euismod orci id consectetur. In vitae lacinia leo. In et purus ligula. Nulla rutrum pellentesque diam ac eleifend. Aenean viverra faucibus aliquam.

    Aliquam volutpat felis a hendrerit vestibulum. Nulla vel erat justo. Phasellus metus nulla, eleifend ut magna quis, convallis luctus quam. Fusce ac posuere eros, cursus lacinia arcu. Fusce elementum luctus ante, a varius elit pulvinar et. Nunc ultricies non felis id semper. In ultricies est eget tincidunt sodales. Proin ut tincidunt ipsum. Donec elementum tortor eu congue sodales. Aenean ultrices, leo eu rhoncus varius, eros nisi sagittis mi, vel ultrices mi magna eu justo. Cras eget erat libero. Nam sagittis neque et finibus pretium. Fusce ac mauris eu sapien facilisis consectetur. Sed sed ullamcorper nibh, eget bibendum ex. Donec vehicula orci erat.

  • CloseRead

    Secondary Analysis

  • CloseRead

    Tertiary Portals

  • CloseRead

    Quality Checking

OK

We use cookies on this site to enhance your user experience of this website. By clicking any link on this page, you are giving your consent for us to set cookies.